Currently Enrolling Study

TMG/EEG study - Healthy Volunteers

This study uses a procedure called Transcranial Magnetic Stimulation (TMS) to see how the brain changes when a person is undergoing sedation. A non-invasive procedure called electroencephalography is used to record the changes.

People in this study will be given midazolam, which is an anesthetic commonly used for surgical procedures. They will also have one MRI to find out what area of the brain to study.

Healthy right-handed men aged 21-35 who do not smoke or have any metallic implants may be eligible for this study.

There are 3 study visits, one each at the Waisman Center, the Wisconsin Psychiatric Institute (WisPIC), and UW Hospital. Visits will take from 1 to 8 hours (for a total of about 10-12 hours).

There will be no cost to you for being in this study. You will be reimbursed $250 to complete the study. Travel and parking costs may also be reimbursed.

For more info, contact Gurkit Miranpuri at (608) 265-0633 or gmiran@clinicaltrials.wisc.edu

You can also contact the Office of Clinical Trials at 1-800-755-5667 or ctrials@clinicaltrials.wisc.edu

ALS, Parkinson’s Disease, and healthy volunteers

The NINDS-CRA study involves a national repository of blood samples and health information from people with amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and other neurological diseases.  Genetic information obtained from the blood (DNA) and health information will be made available to researchers all over the world who are trying to learn more about the cause of neurological diseases. We are also collecting blood and information from people who do not have any neurological diseases, so that researchers can compare DNA from “normal” people to DNA from people with neurological disorders.

Subjects without neurological disorders cannot have a history of migraines headaches or have had a brain aneurysm. They also cannot participate if a parent or sibling has a neurological disorder.

Participants will not be paid. A blood sample and 20 minutes of your time could help further understanding of neurological diseases.

For more info, contact Nick Ruys at (608) 263-9602 or 1-800-755-5667. 
You can also email us at ctrials@clinicaltrials.wisc.edu.

Deep Brain Stimulation (DBS) in Parkinson’s Disease

Deep brain stimulation (DBS) is a surgical procedure sometimes used in people with Parkinson’s disease.  The purpose of the DBS-Parkinson’s study is to see if a new investigational DBS device, used in combination with standard drug treatments, can reduce advanced Parkinson’s disease symptoms such as slowness, stiffness, and/or shaking movements. 

If you are between the ages of 18 and 80, were diagnosed with Parkinson’s disease at least 5 years ago, have shown benefit now or in the past from levodopa treatment, and have difficulty performing voluntary movements during waking hours, you may be eligible for this study.

People in this study will have 2-3 pre-surgery clinic visits and 4 follow-up clinic visits over a 12 month time period. You may be paid up to $1200.00 if you finish this study.

For more info, contact Christa Tober, OTR, MS at (608) 265-8765 or 1-800-755-5667.  You can also email us at ctrials@clinicaltrials.wisc.edu.